Nutritional Challenge and Its Health Effects

In their article, Abbondante et al. argue that alterations in a person’s nutrition affect the presence and characteristics of metabolites in the serum and liver controlled by circadian rhythms, and the effects are different for the two tissues (2824). The importance of the study is explained by the widespread practice of analyzing metabolites in the serum as part of diagnostic procedures; however, nutrition is not considered as a significant factor to a necessary effect. Upon experimenting on mice, the authors show that a high fat diet results in decreasing the rhythmicity of serum metabolite, while the dynamics of circadian metabolomics in the liver is different, which confirms “a circadian misalignment” (2812) between the two tissues.

The results are supported by presenting detailed research and properly recording the results. This makes the conclusion reliable and applicable to practices that are used in diagnostics and associated with serum examinations. Serum metabolomics had been viewed as a promising field because it could be used to examine perturbations associated with early biochemical changes; therefore, predictors and markers could be developed that would allow administering appropriate treatment sooner and gaining a better understanding of how diseases affect the human organism on the biochemical level (Zhang et al. 1239). However, Abbondante et al. showed that nutritional challenge can disrupt the circadian rhythm (2825), which is why more critical approaches to serum examination and diagnostics should be developed that would recognize the role of nutrition. Moreover, the authors identified specific serum metabolites that indicate risks of various metabolic disorders and analyzed them from the proposed perspective of different effects of nutritional challenge across different tissues. The role of nutrition was previously recognized (Zhang et al. 1240), but the difference between effects on the serum and liver had not been properly addressed. The results of the addressed study are valid and beneficial in terms of improving clinical practices.

Works Cited

Abbondante, Serena, et al. “Comparative Circadian Metabolomics Reveal Differential Effects of Nutritional Challenge in the Serum and Liver.” Journal of Biological Chemistry, vol. 291, no. 6, 2016, pp. 2812-2828.

Zhang, Aihua, et al. “Serum Metabolomics as a Novel Diagnostic Approach for Disease: A Systematic Review.” Analytical and Bioanalytical Chemistry, vol. 404, no. 4, 2012, pp. 1239-1245.

Calculate the price
Make an order in advance and get the best price
Pages (550 words)
$0.00
*Price with a welcome 15% discount applied.
Pro tip: If you want to save more money and pay the lowest price, you need to set a more extended deadline.
We know how difficult it is to be a student these days. That's why our prices are one of the most affordable on the market, and there are no hidden fees.

Instead, we offer bonuses, discounts, and free services to make your experience outstanding.
How it works
Receive a 100% original paper that will pass Turnitin from a top essay writing service
step 1
Upload your instructions
Fill out the order form and provide paper details. You can even attach screenshots or add additional instructions later. If something is not clear or missing, the writer will contact you for clarification.
Pro service tips
How to get the most out of your experience with Online Academic Experts
One writer throughout the entire course
If you like the writer, you can hire them again. Just copy & paste their ID on the order form ("Preferred Writer's ID" field). This way, your vocabulary will be uniform, and the writer will be aware of your needs.
The same paper from different writers
You can order essay or any other work from two different writers to choose the best one or give another version to a friend. This can be done through the add-on "Same paper from another writer."
Copy of sources used by the writer
Our college essay writers work with ScienceDirect and other databases. They can send you articles or materials used in PDF or through screenshots. Just tick the "Copy of sources" field on the order form.
Testimonials
See why 20k+ students have chosen us as their sole writing assistance provider
Check out the latest reviews and opinions submitted by real customers worldwide and make an informed decision.
Management
Love this writer!!! Great work
Customer 452597, April 5th, 2021
Emergency Management
Thanks
Customer 453015, October 28th, 2022
Business and administrative studies
Excellent work and done hen needed and they always get it done ahead of time
Customer 453201, October 17th, 2022
Nursing
It was a very long paper, but she followed all the instructions, and she even finished the paper 5 days before the due date. Will write an essay with her again, thanks!
Customer 452967, November 27th, 2021
Emergency Management
Overall, I think it's a great service. I have yet to submit the assignment, so I don't know what kind of grade I'll get. But customer service was excellent. Reviews were made and the assignment proofed for satisfaction.
Customer 453015, December 15th, 2021
Psychology
thank you!
Customer 452947, October 21st, 2021
Business and administrative studies
excellent
Customer 453201, October 22nd, 2022
History
Looks great and appreciate the help.
Customer 452675, April 26th, 2021
Social Work and Human Services
Although it took 2 revisions I am satisfied but I did receive it late because of that.
Customer 452603, March 25th, 2021
Marketing
I initially had a hard time opening the paper but finally was able to get what i needed.
Customer 453217, October 31st, 2022
Business and administrative studies
awesome work
Customer 453201, June 15th, 2022
History
Don't really see any of sources I provided, but elsewise its great, thank you!
Customer 452697, May 8th, 2021
11,595
Customer reviews in total
96%
Current satisfaction rate
3 pages
Average paper length
37%
Customers referred by a friend
OUR GIFT TO YOU
15% OFF your first order
Use a coupon FIRST15 and enjoy expert help with any task at the most affordable price.
Claim my 15% OFF Order in Chat
Live ChatWhatsApp