Describe how the culling and elision procedures would be applied to a case where multiple optimal…

Describe how the culling and elision procedures would be applied to a case where multiple optimal alignments were obtained by use of the same scoring function.

Take the following sequence alignments for three different alignment costs.

(a) Cull them and characterize how many positions were culled as a result of being alignment-ambiguous.

(b) Elide them and characterize the weights of each column in the two initial alignments.

alignment 1

sequence 1      CGATCGATCA

sequence 2      CGA-CG-TCA

sequence 3      CGACCGA-CA

sequence 4      CGAT-GACCA

alignment 2

sequence 1       CGATCGATCA

sequence 2       CGAC-G-TCA

sequence 3       CGACCGA-CA

sequence 4       CGAT-GACCA

alignment 3

sequence 1      CGATCGATCA

sequence 2      CGA-CG-TCA

sequence 3      CGACCGA-CA

sequence 4      CGATGAC-CA

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