66 Sepsis Research Topics & Essay Examples

Table of Contents
Definition Sepsis is a severe human infectious disease that develops as a systemic inflammatory reaction when infectious agents or their toxins enter the bloodstream.
Specialty Hematology and microbiology
History The designation of the term “sepsis” comes from the Greek word meaning “putrefaction” or “decay,” and was first used by Homer over 2,700 years ago. N.I. Pirogov was the first to determine the significance of the primary focus of infection in the pathogenesis of wound sepsis, described in detail its general and local manifestations. He also classified sepsis and formulated the principles of its treatment that were advanced for its time. Finally, in 1914, Schottmüller for the first time proposed to associate sepsis with the host’s response to infection.
Symptoms The clinical picture consists of symptoms of general intoxication and manifestations of the disease caused by infectious foci. Intoxication is manifested by severe weakness, loss of appetite, fever with chills, tachycardia, low blood pressure, and shortness of breath.
Causes Any type of infection – bacterial, viral, or fungal – can lead to sepsis. However, the most likely options are: pneumonia, infections of the digestive system, kidneys, bladder, and other parts of the urinary system, as well as blood infection (bacteremia).
Prevention Prevention of sepsis is based on the correct and timely treatment of local purulent processes, as well as compliance with aseptic conditions during home medical procedures, including injections.
Diagnostic Method Diagnosis of sepsis is based on the clinical picture of the disease, the detection of pathogenic microorganisms in the blood, and the detection of septic foci in various organs and tissues.
Treatment Treatment of sepsis is complex, including massive antibacterial or antifungal therapy, detoxification therapy. In some cases, transfusion of blood components, the use of renal replacement therapy, artificial nutrition, and artificial respiration may be required.
Duration Sepsis is characterized by a rapid and severe progressive course, as well as the absence of a tendency to spontaneous recovery. The patient cannot recover without medical intervention, often this includes a general intensive treatment and surgery.
Prognosis The prognosis for any form of sepsis is always serious. The sooner treatment is started, the higher the chance of a full recovery. The discharge of the patient from the hospital does not mean a complete cure. After discharge from the hospital, further observation is required at the place of residence, respect for health, and timely seeking medical help.
Complications Sepsis can progress to septic shock, when certain changes occur in the circulatory system and body cells that interfere with the delivery of oxygen and other substances to the tissues. Septic shock is more likely to cause death than sepsis.
Frequency in Population In 2017, an estimated 48,9 million incident cases of sepsis were recorded worldwide.
Deaths 11,0 million sepsis-related deaths were reported, representing 19,7% of all global deaths.
Society There is not much knowledge about sepsis in general population besides referring to it as “blood poisoning”. Usually, sepsis is viewed as a possible consequence of improper open injury hygiene.

Sepsis Research Papers Examples

  1. The patient is likely to suffer from sepsis that was probably caused by a certain abdominal infection. The patient should receive sepsis therapy as soon as possible.
  2. Every year, more than a million US citizens suffer from sepsis, a body’s response to an infection that has escalated to a life-threatening condition.
  3. Sepsis is a considerable bother for pediatric department workers since neonatal sepsis is among the primary causes of newborn mortality.

Best Sepsis Essay Titles

  1. Clinical Presentation and Outcomes Among Children With Sepsis Presenting to a Public Tertiary Hospital in Tanzania
  2. Trimetazidine Attenuates Cardiac Dysfunction in Endotoxemia and Sepsis by Promoting Neutrophil Migration
  3. Sepsis-induced Cardiomyopathy: Mechanisms and Treatments
  4. CSF2 Attenuated Sepsis-induced Acute Kidney Injury by Promoting Alternative Macrophage Transition
  5. Inflammatory Mediator Profiles Differ in Sepsis Patients With and Without Bacteremia
  6. The Critical Roles and Mechanisms of Immune Cell Death in Sepsis
  7. Translational Insights Into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma
  8. Poor Compliance With Sepsis Guidelines in a Tertiary Care Children’s Hospital Emergency Room
  9. Diabetes and Sepsis: Risk, Recurrence, and Ruination
  10. The Yin and Yang of Tyrosine Kinase Inhibition During Experimental Polymicrobial Sepsis
  11. Antimicrobial Peptides for Gram-negative Sepsis: A Case for the Polymyxins
  12. Severe Sepsis Survival: From Hopelessness to Hopefulness
  13. Exome Sequencing Reveals Primary Immunodeficiencies in Children With Community-acquired Pseudomonas Aeruginosa Sepsis
  14. Pediatric Severe Sepsis Prediction Using Machine Learning
  15. Sepsis: The Main Cause of Death in Intensive Care Units
  16. Emodin Combined With Nanosilver Inhibited Sepsis by Anti-inflammatory Protection
  17. Sepsis Patients With First and Second-hit Infections Show Different Outcomes Depending on the Causative Organism
  18. Sepsis: Systemic Inflammatory Response Syndrome and Higher Mortality Rates
  19. COVID-19 Sepsis and Microcirculation Dysfunction
  20. Sepsis: Inflammation and White Cell Count
  21. Endothelial Activation: The Ang & Tie Axis in Sepsis
  22. Puerperal Sepsis: History, Causes, and Interventions
  23. Distinguishing Sepsis From Infection by Neutrophil Dysfunction: A Promising Role of CXCR2 Surface Level
  24. Sepsis-like Systemic Inflammation Induced by Nano-sized Extracellular Vesicles From Feces
  25. Exome Sequencing Reveals Primary Immunodeficiencies in Children With Community-acquired Pseudomonas Aeruginosa Sepsis
  26. New Insights for C5a and C5a Receptors in Sepsis
  27. Sepsis and Nosocomial Infection: Patient Characteristics, Mechanisms, and Modulation
  28. Chronic Toxoplasma Gondii Infection Exacerbates Secondary Polymicrobial Sepsis
  29. Cell-Free Plasma DNA as a Predictor of Outcome in Severe Sepsis and Septic Shock
  30. Coalition for Sepsis Survival Marketing Plan
  31. Ager-mediated Lipid Peroxidation Drives Caspase-11 Inflammasome Activation in Sepsis
  32. Infection, Sepsis and the Inflammatory Response: Mechanisms and Therapy
  33. Neonatal Sepsis Diagnosis Decision-making Based on Artificial Neural Networks
  34. Sepsis: Shock and Tissue Perfusion
  35. Adrenomedullin and Adrenomedullin-targeted Therapy as Treatment Strategies Relevant for Sepsis
  36. Adrenal Gland Microenvironment and Its Involvement in the Regulation of Stress-induced Hormone Secretion During Sepsis
  37. Platelets and Intravascular Immunity: Guardians of the Vascular Space During Bloodstream Infections and Sepsis
  38. Autonomic Nervous System Dysfunction in Pediatric Sepsis
  39. Ferritin Light Chain Confers Protection Against Sepsis-induced Inflammation and Organ Injury
  40. Sepsis: Childbirth and Early-Onset Bacterial Sepsis

❓ Sepsis Research Questions

  1. What Is the Epidemiology and Immunological Pathogenesis of Viral Sepsis?
  2. How Does Polymicrobial Sepsis Impair Antigen-Specific Memory CD4 T Cell Immunity?
  3. What Is the Prevention, Detection, and Treatment of Sepsis in ICU Patients?
  4. What Are the Causes and Effects of Contracting Sepsis?
  5. What Is the Rationale for the Dose of Amoxicillin for Neonatal Sepsis When Referral Is Not Possible?
  6. What Is the Efficacy of Precision Immunotherapy for Sepsis?
  7. What Is Concomitant Sepsis?
  8. What Is the Clinical Treatment for Sepsis?
  9. Where Sepsis and Antimicrobial Resistance Countermeasures Converge?
  10. What Is the Prevalence, Risk Factors, and Outcomes of Sepsis in Critically Ill Patients in China?
  11. What Are the Causes and Treatments for Sepsis?
  12. Are Corticosteroids Beneficial for Sepsis and Septic Shock?
  13. What Is the Polygenic Risk Score for Early Predictive Risk of Sepsis in the Polytrauma Screening Cohort?
  14. What Is the Diagnosis, Management, and Treatment of Sepsis?
  15. Health Care-Associated Pneumonia and Sepsis Biology?
  16. What Are the Arguments for Adaptive Clinical Trials in Sepsis?
  17. How To Identify and Treat Sepsis in the Early Stages?
  18. What Are the Early Inflammatory Markers for the Diagnosis of Late Neonatal Sepsis?
  19. Is Precision Medicine Effective for Neonatal Sepsis?
  20. What Is the Beneficial Effect of Activated Protein C in the Treatment of Severe Sepsis?
  21. Non-neuronal Acetylcholine: The Missing Link Between Sepsis, Cancer, and Delirium?
  22. What Is Blood Poisoning, Also Called Septicemia or Sepsis?
  23. What Is the Sepsis Recognition Sorting Tool?

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